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Comment & Response
November 2015

Measurement Methodology: What Does Blood Pressure Mean in the PARTAGE Study?—Reply

Author Affiliations
  • 1Department of Geriatrics, University Hospital of Nancy, Nancy, France
  • 2Inserm, U1116, Université de Lorraine, Nancy, France
  • 3Inserm Clinical Investigation Centre, CIC-P 1433, Université de Lorraine, and CHU de Nancy, France
JAMA Intern Med. 2015;175(11):1860. doi:10.1001/jamainternmed.2015.4630

In Reply We would like to thank Stergiou et al for their interest in our article.

The PARTAGE study is a pragmatic analysis of how we assess cardiovascular risk in elderly individuals living in nursing homes, a dramatically growing population in all developed societies. We note that antihypertensive treatment is based on blood pressure (BP) measured by the personal physician in the nursing home. In addition to this standard clinical measurement, we proposed assisted self-measurements by applying the precise protocol of the French Society of Hypertension (3 measurements in the morning and 3 measurements in the evening over the course of 3 days, totaling 18 measurements). Following this procedure, we made 2 key observations: (1) BP values recorded with standard clinical procedures were very similar to those obtained with multiple 3-day morning and evening measurements,1 and (2) when using one or the other BP-measurement method, subjects with low systolic BP (<130 mm Hg) receiving combination antihypertensive therapy displayed a statistically significant and clinically relevant 80% higher mortality compared with all other groups of individuals.2

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