Obesity has many adverse effects on cardiovascular risk factors, such as dyslipidemia, metabolic syndrome or type 2 diabetes mellitus, and hypertension, as well as on cardiovascular structure and function. Therefore, it is not surprising that the prevalence of cardiovascular diseases is markedly increased in the setting of overweight and obesity.1 Considering that increased fat accumulation causes increases in total blood volume, stroke volume, and cardiac output, it is expected that obesity markedly increases the prevalence of hypertension and places a heavy strain on the left and right sides of the heart, which not surprisingly increases the prevalence of heart failure, even in a setting of metabolically healthy obesity.1
Lavie CJ, Parto P, Archer E. Obesity, Fitness, Hypertension, and Prognosis: Is Physical Activity the Common Denominator? JAMA Intern Med. 2016;176(2):217–218. doi:10.1001/jamainternmed.2015.7571
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