During the last 20 years, there have been substantial changes in the legal status and public perception of marijuana in the United States. Decriminalization, medical dispensaries with marijuana for those with a physician’s note, and legalization of marijuana in several states have resulted in increased availability and more relaxed views toward marijuana use. However, to our knowledge, relatively little research has been done on the risks of long-term marijuana use.
In this issue of JAMA Internal Medicine, Auer and colleagues1 report an association between cumulative lifetime marijuana exposure and cognitive performance in a prospective study of 3385 middle-aged adults who were followed up for 25 years. Their findings suggest that those who used marijuana on a long-term daily basis have poorer verbal memory in middle age than do their peers who have not smoked marijuana habitually.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Hall W, Lynskey M. Long-term Marijuana Use and Cognitive Impairment in Middle Age. JAMA Intern Med. 2016;176(3):362–363. doi:10.1001/jamainternmed.2015.7850
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: