In Reply We appreciate the interest in our work from Zhou and colleagues. The China Kadoorie Biobank is a large population-based prospective cohort study of 0.5 million adults ages 35 to 74 years (when recruited during 2004-2008) from 10 diverse regions of China.1 We reported that about one-third of the participants had hypertension at recruitment, but less than 5% of these hypertensives had their blood pressure properly controlled (<140 mm Hg systolic and <90 mm Hg diastolic blood pressure).1 We estimated that if these findings were broadly representative, then approximately 750 000 cardiovascular deaths could be attributed to uncontrolled hypertension in China in 2010.