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Comment & Response
December 2016

Association of Specific Dietary Fats With Mortality

Author Affiliations
  • 1Independent Researcher and Author, Lund, Sweden
  • 2Nagoya City University, Kinjo Gakuin University, Japan
  • 3Institute for Consumer Science and Human Life, Kinjo Gakuin University, Japan
  • 4Institute of Clinical Exercise and Health Science, University of the West of Scotland, Hamilton, Lanarkshire
JAMA Intern Med. 2016;176(12):1878. doi:10.1001/jamainternmed.2016.7125

To the Editor In their study of the influence of diet on mortality in a recent issue of JAMA Internal Medicine Wang et al1 argue for a higher intake of ω-6 polyunsaturated fatty acids (PUFA) and a lower intake of saturated fatty acids (SFA), contradicting the better evidence having shown that such a diet is of no benefit. They weigh their own analysis of 2 observational studies including about 126 000 individuals greater than the meta-analysis by Chowdhury et al2 of 46 observational studies and 27 trials including 5 times more participants that found no evidence for their proposition. Wang et al have also ignored a meta-analysis by Siri-Tarino et al3 of 21 cohort studies including almost 350 000 participants that found no association between intake of SFA and mortality.

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