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Evidence to Practice
March 2017

Midlife Approaches to Prevention of Ill Health in Later Life

Author Affiliations
  • 1Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, England
JAMA Intern Med. 2017;177(3):423-424. doi:10.1001/jamainternmed.2016.8849

The Cambridge Institute of Public Health conducted 3 rapid evidence reviews to inform the National Institute for Health and Care Excellence (NICE) guideline on midlife approaches to prevent or delay onset of dementia, disability, and frailty (DDF) published on October 20, 2015.1

The full version of the guideline and its supporting documents contain details of the methods used to derive the recommendations.1 The effectiveness of individually directed midlife (40-64 years) interventions to increase the uptake and maintenance of healthy behaviors are summarized herein. No studies reported on the effect of midlife interventions on DDF outcomes.2