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Comment & Response
April 2017

Incorrect Conclusions Concerning Antibiotics and Asthma Exacerbation

Author Affiliations
  • 1National Heart and Lung Institute, Imperial College London, London, England
  • 2Respiratory Medicine, Heart of England Foundation Trust, Birmingham, England
  • 3Respiratory Medicine, Portsmouth Hospitals NHS Trust, Portsmouth, England
JAMA Intern Med. 2017;177(4):598. doi:10.1001/jamainternmed.2017.0110

To the Editor We strongly support antibiotic stewardship, but we disagree with the statement, “Johnston and colleagues1 demonstrate that antibiotics for asthma exacerbation do not improve outcomes,”2(p1649) from an Invited Commentary by Mehrotra and Linder in a recent issue of JAMA Internal Medicine. It is true that the AZALEA study1 showed no benefit in primary or secondary outcomes; however, the statement by Mehrotra and Linder2 is not supported by the data we reported.

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