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In Reply Leite and colleagues raise the hypothesis that part of the observed effect in the cohort in our study1 may be due to donor obesity. This hypothesis is interesting and potentially important at a population level. Although the reporting of body mass index is currently not available in our donor cohort, we obtained the prevalence of obesity estimates from Statistics Canada2 to evaluate how obesity could influence our results.
Chassé M, Fergusson DA. Blood Donor Characteristics On Transfusion Outcomes—Should Obesity Be Assessed in Future Clinical Trials?—Reply. JAMA Intern Med. 2017;177(4):599–600. doi:10.1001/jamainternmed.2017.0245
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