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Comment & Response
Less Is More
August 2017

Discrepant Expectations About Benefits and Harms—Reply

Author Affiliations
  • 1Centre for Research in Evidence-Based Practice, Faculty of Health Sciences and Medicine, Bond University, Queensland, Australia
JAMA Intern Med. 2017;177(8):1226-1227. doi:10.1001/jamainternmed.2017.2389

In Reply We thank Dr Braillon for his comments. First, we agree that innumeracy and naiveté about clinical epidemiology concepts are some of the underlying contributions to the misperceptions that we report in our systematic review.1 Clinician illiteracy in health statistics has been articulated previously.2,3 However, we disagree that the benefits of interventions are certain while the harms are only a potential risk. Few interventions have certain benefits: there is both the chance of benefit and the chance of harm from most interventions.

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