To the Editor In the SPRINT (Systolic Blood Pressure Intervention Trial) randomized clinical trial published in a recent issue of JAMA Internal Medicine, Odden and colleagues1 conclude that intensive blood pressure lowering was not associated with changes in gait speed or transitions in mobility status among adults 75 years or older. SPRINT1 is an important randomized clinical trial that should have a substantial influence on future clinical practice. However, it was not well designed to test the effect of intensive blood pressure control on gait speed and mobility limitation in older adults.
Zhang Y, Huang X, Chen L. Intensive Blood Pressure Control on Gait Speed and Mobility Limitation for Older Adults. JAMA Intern Med. 2017;177(9):1395–1396. doi:https://doi.org/10.1001/jamainternmed.2017.3001
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