To the Editor Maintaining optimal blood pressure in patients without diabetes with chronic kidney disease (CKD) has always been controversial. In a systematic review and meta-analysis published in a recent issue of JAMA Internal Medicine, Tsai et al1 assessed the clinical data of 8127 patients; they focused on detecting an association between intensive blood pressure control and renal outcomes in patients without diabetes with CKD. Consequently, no significant difference in major renal outcomes was found between intensive (<130/80 mm Hg) and standard BP control (<140/90 mm Hg) groups during a median follow-up of 3.3 years. Nevertheless, nonblack patients or those with higher levels of proteinuria were found to benefit from the intensive BP-lowering strategy.
Ardalan M, Golzari SEJ. Intensive Blood Pressure Control in Autosomal Dominant Polycystic Kidney Disease—How Safe Is It? JAMA Intern Med. 2017;177(11):1694. doi:10.1001/jamainternmed.2017.4907
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: