In Reply We would like to thank Drs Ardalan and Golzari for their opinions concerning intensive blood pressure (BP) control in patients with autosomal dominant polycystic kidney disease (ADPKD). Hypertension is common, occurs early, and is associated with the loss of renal function in patients with ADPKD.1,2 Despite the importance of BP control in patients with chronic kidney disease, the role of intensive BP-lowering strategy in delaying the progression of ADPKD is not clear.
Tsai W, Chien K, Wu H. Intensive Blood Pressure Control in Autosomal Dominant Polycystic Kidney Disease—How Safe Is It?—Reply. JAMA Intern Med. 2017;177(11):1695–1696. doi:10.1001/jamainternmed.2017.4925
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