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Comment & Response
December 2017

Search Images and Extrapolation Risk—Reply

Author Affiliations
  • 1Department of Urology, Weill Cornell Medicine, New York, New York
  • 2Departments of Surgery and Pediatrics, Center for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
JAMA Intern Med. 2017;177(12):1871. doi:10.1001/jamainternmed.2017.4922

In Reply We read with great interest the contrasting views from Dr Rothschild and Dr Brown suggesting that evaluation of asymptomatic microscopic hematuria is either insufficiently sensitive or too aggressive for the detection of genitourinary pathology. The crux of this debate pertains to the yield and potential value of early detection of genitourinary conditions in the setting of asymptomatic microscopic hematuria. Our Original Investigation1 focused on detection of malignancy, which we believe is paramount, since patients with urothelial cancer may have progression of disease by the time they develop symptoms.2,3

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