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Comment & Response
March 2018

Coronary Computed Tomographic Angiography and Potential for Overtreatment—Reply

Author Affiliations
  • 1Departments of Medicine and Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania
  • 2Louisville Cardiology Group at Baptist Health, Louisville, Kentucky
JAMA Intern Med. 2018;178(3):436-437. doi:10.1001/jamainternmed.2017.8664

In Reply We thank Tsarpalis for his letter emphasizing the importance of discussing overtreatment with patients. But we disagree with his implicit acceptance that excess revascularization in the coronary computed tomographic angiography (CCTA) group may have contributed to the signal of reduced myocardial infarction (MI) in our Original Investigation.1 We are not confident in the MI-reduction signal.

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