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Research Letter
Less Is More
March 26, 2018

Antibiotic Therapy Duration in US Adults With Sinusitis

Author Affiliations
  • 1Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
JAMA Intern Med. Published online March 26, 2018. doi:10.1001/jamainternmed.2018.0407

Sinusitis is the most common condition for which outpatient antibiotic therapy is prescribed in the United States.1 Sinusitis antibiotic stewardship efforts have largely focused on whether to prescribe antibiotics and on the selection of appropriate antibiotics.1,2 When antibiotics are indicated for the treatment of acute bacterial sinusitis, the Infectious Diseases Society of America evidence-based clinical practice guidelines recommend 5 to 7 days of therapy for patients with a low risk of antibiotic resistance who have a favorable response to initial therapy.3 Guideline-concordant treatment duration may represent a stewardship opportunity. Our objective was to describe the duration of antibiotic therapy for acute sinusitis in adult outpatients.

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