Sinusitis is the most common condition for which outpatient antibiotic therapy is prescribed in the United States.1 Sinusitis antibiotic stewardship efforts have largely focused on whether to prescribe antibiotics and on the selection of appropriate antibiotics.1,2 When antibiotics are indicated for the treatment of acute bacterial sinusitis, the Infectious Diseases Society of America evidence-based clinical practice guidelines recommend 5 to 7 days of therapy for patients with a low risk of antibiotic resistance who have a favorable response to initial therapy.3 Guideline-concordant treatment duration may represent a stewardship opportunity. Our objective was to describe the duration of antibiotic therapy for acute sinusitis in adult outpatients.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
King LM, Sanchez GV, Bartoces M, Hicks LA, Fleming-Dutra KE. Antibiotic Therapy Duration in US Adults With Sinusitis. JAMA Intern Med. Published online March 26, 2018. doi:10.1001/jamainternmed.2018.0407
Customize your JAMA Network experience by selecting one or more topics from the list below.