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July 9, 2018

Devolution and Devaluation of Fecal Leukocyte TestingA 100-Year History

Author Affiliations
  • 1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas
  • 2Parkland Health and Hospital Systems, Dallas, Texas
  • 3Division of Gastroenterology, University of Texas Southwestern Medical Center, Dallas
JAMA Intern Med. Published online July 9, 2018. doi:10.1001/jamainternmed.2018.3150

In 1918, Willmore and Shearman reported on the stool examinations of 1165 Egyptian patients with dysentery and provided one of the first accounts of stool cellular exudates.1 They detailed how the distribution and morphologic features of cells in stool exudate could differentiate amoebic and bacillary dysentery (Figure) and argued that this method was more rapid and accurate than stool culture.

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