In 1918, Willmore and Shearman reported on the stool examinations of 1165 Egyptian patients with dysentery and provided one of the first accounts of stool cellular exudates.1 They detailed how the distribution and morphologic features of cells in stool exudate could differentiate amoebic and bacillary dysentery (Figure) and argued that this method was more rapid and accurate than stool culture.
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Gupta A, Johnson DH, Agrawal D. Devolution and Devaluation of Fecal Leukocyte TestingA 100-Year History. JAMA Intern Med. Published online July 09, 2018. doi:10.1001/jamainternmed.2018.3150
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