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Comment & Response
July 2018

Standardization of Continuous Renal Replacement Therapy—Reply

Author Affiliations
  • 1Cedars-Sinai Medical Center, Los Angeles, California
JAMA Intern Med. 2018;178(7):1003. doi:10.1001/jamainternmed.2018.2676

In Reply We thank Chang et al for their interest and insight regarding our evidence-based approach to improve continuous renal replacement therapy (CRRT) utilization at our institution.

Although the average duration of therapy per patient and the average direct cost per patient both decreased, the average direct cost per day using CRRT remained similar preintervention and postintervention. We believe that this change in treatment duration reflects the results of our efforts to encourage appropriate utilization of CRRT. Because we did not change the amount of resources used to provide 1 patient-day’s duration of treatment, the average direct cost per day on CRRT remained the same.

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