Good Clinical Practice in Diagnosis of Vulvovaginal Symptoms

To the Editor We read with great interest the recent report by Mitchell and colleagues regarding the efficacy of topical low-dose vaginal estrogen vs topical vaginal moisturizer or placebo for treating postmenopausal vulvovaginal symptoms.^1(p681) We are concerned with the authors’ conclusion that “…neither prescribed vaginal estradiol tablet nor over-the-counter vaginal moisturizer provides additional benefit over placebo vaginal tablet and gel in reducing postmenopausal vulvovaginal symptoms.”¹