A man in his 70s with a history of type 2 diabetes and hypertension presented with syncope. He reported symptoms while ambulating with sudden onset of weakness and diaphoresis followed by loss of consciousness for several minutes. There was no reported seizure activity, and he denied preceding chest pain, palpitations, or shortness of breath. After regaining consciousness, he returned to baseline.
In the emergency department, the patient was alert and asymptomatic. Electrocardiogram (ECG) showed normal sinus rhythm, right bundle branch block (RBBB), and left anterior fascicular block (LAFB) (Figure 1). Vital signs included blood pressure, 151/83 mm Hg; heart rate, 72 beats per minute; respiratory rate, 18 per minute; and oxygen saturation, 98% while breathing ambient air. Orthostatic assessment revealed no significant decrease in blood pressure with sitting or standing. Physical examination, including cardiopulmonary and neurology screen, had normal results. Laboratory data revealed normal glucose, electrolytes, and serial cardiac troponin I of less than 0.02 ng/mL (reference range, <0.05 ng/mL; 1-to-1 correspondence with nanograms per liter). Transthoracic echocardiogram revealed a left ventricular ejection fraction of 55% with normal left ventricular wall motion and mild concentric left ventricular hypertrophy.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Pham TH, Amsterdam E, Glassy MS. Syncope With Bifascicular Block Due to Infra-Hisian Wenckebach Conduction Abnormality. JAMA Intern Med. Published online August 20, 2018. doi:10.1001/jamainternmed.2018.3951
Customize your JAMA Network experience by selecting one or more topics from the list below.