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Research Letter
October 2018

Association of Nausea and Vomiting in Pregnancy With Prenatal Marijuana Use

Author Affiliations
  • 1Division of Research, Kaiser Permanente Northern California, Oakland
  • 2Early Start Program, Kaiser Permanente Northern California, Oakland
  • 3Regional Offices, Kaiser Permanente Northern California, Oakland
JAMA Intern Med. 2018;178(10):1423-1424. doi:10.1001/jamainternmed.2018.3581

Use of marijuana, an antiemetic, is increasing among pregnant women,1,2 and data from 2 small surveys3,4 indicate that women self-report using marijuana to alleviate nausea and vomiting in pregnancy (NVP). To date, only 1 epidemiologic study5 has examined whether women with NVP are at elevated risk of using marijuana. The study of 4735 pregnant women in Hawaii5 from 2009 through 2011 found that self-reported prenatal marijuana use was more prevalent among those with (3.7%) vs without (2.3%) self-reported severe nausea during pregnancy. We used data from a large California health care system with standard universal screening for prenatal marijuana use via self-report and urine toxicologic tests from January 1, 2009, through December 31, 2016, to test whether prenatal marijuana use is elevated among females with a diagnosis of NVP.

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