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Research Letter
December 2018

Prevalence of Financial Conflicts of Interest Among Authors of Clinical Guidelines Related to High-Revenue Medications

Author Affiliations
  • 1Division of Gastroenterology, St Michael’s Hospital, Toronto, Ontario, Canada
  • 2Department of Medicine, University of Toronto, Toronto, Ontario, Canada
JAMA Intern Med. 2018;178(12):1712-1715. doi:10.1001/jamainternmed.2018.5106

The presence of financial conflicts of interest in clinical practice guidelines (CPGs) may affect the objectivity of these documents. Although the National Academy of Medicine has created policies to limit industry influence on the development of CPGs, guidelines rarely adhere to these policies.1 Moreover, CPG authors may have undeclared financial conflicts of interest.2 We hypothesized that undeclared industry payments would be highly prevalent among authors of CPGs related to high-revenue medications, and we quantified the presence and extent of these payments.

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