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Bikdeli B, Wang Y, Jimenez D, et al. Association of Inferior Vena Cava Filter Use With Mortality Rates in Older Adults With Acute Pulmonary Embolism. JAMA Intern Med. 2019;179(2):263–265. doi:10.1001/jamainternmed.2018.5287
Acute pulmonary embolism (PE) is a common cause of morbidity and mortality in older adults.1 Inferior vena cava (IVC) filters are frequently used to prevent subsequent PE; nearly 1 in 6 of elderly Medicare fee-for-service (FFS) beneficiaries with PE received an IVC filter.2 However, the evidence supporting device efficacy and safety is scant.3 In recent years, the US Food and Drug Administration raised concerns about the safety of IVC filters, and some studies have indicated a temporal decrease in the use of this technology.4 Meanwhile, some investigators, using administrative data with limited adjustments, have found that the use of IVC filters was associated with reduced mortality rates, recommending their use.5 This study sought to determine the association between use of IVC filters and mortality rates in Medicare FFS beneficiaries with PE using 3 distinct statistical approaches.
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