Before 2009, etanercept, infliximab, and adalimumab were the only tumor necrosis factor (TNF) inhibitors approved by the US Food and Drug Administration for rheumatoid arthritis. Subsequently, 3 therapies have gained US Food and Drug Administration approval: subcutaneous golimumab (April 2009),1 certolizumab pegol (May 2009),2 and intravenous golimumab (July 2013).3 All 6 agents are brand-name drugs. We assessed how the prices of existing TNF inhibitors changed in response to the market entry of new TNF inhibitors.
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San-Juan-Rodriguez A, Prokopovich MV, Shrank WH, Good CB, Hernandez I. Assessment of Price Changes of Existing Tumor Necrosis Factor Inhibitors After the Market Entry of Competitors. JAMA Intern Med. Published online February 18, 2019179(5):713–716. doi:10.1001/jamainternmed.2018.7656
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