To the Editor In a recent Special Communication published in JAMA Internal Medicine,1 Morgan and colleagues reviewed the leading causes of overuse of medical care and concluded that high-sensitivity troponin testing often yields false-positive results because a minority of patients with positive test results are finally diagnosed with myocardial infarction. We believe that this conclusion may be flawed by an incomplete appreciation of cardiac troponins biology.
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Lippi G, Cervellin G. Clinical Interpretation of High-Sensitivity Troponin Testing. JAMA Intern Med. 2019;179(5):725–726. doi:10.1001/jamainternmed.2019.0371
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