In Reply We appreciate the interest by Stein and colleagues in our recent investigation,1 are cognizant of their efforts to generate information related to inferior vena cava (IVC) filters, and would like to provide several clarifications. The goal of our study was to test the association between IVC filter use and short-term and 1-year mortality rates in older adults with pulmonary embolism (PE). Our results, consistent across 3 separate analytical approaches, did not suggest an association between use of IVC filters and reduced mortality rates but, rather, suggested a hypothesis-generating increase.