In Reply We appreciate the comments by Halliday et al regarding our article.1 Concerns of overestimated complication rates were raised, citing the following 4 reasons: representativeness of our study population, unmeasured confounders, relevant time frame for postprocedural complications, and not differentiating between complications with vs without direct association with the invasive diagnostic procedures. Herein, we have summarized our point-by-point response.