[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 18
Citations 0
Comment & Response
October 2019

Studies Making Use of the Same Randomized Clinical Trial Cohorts—Reply

Author Affiliations
  • 1The George Institute for Global Health, University of New South Wales, Newtown, New South Wales, Australia
JAMA Intern Med. 2019;179(10):1447. doi:10.1001/jamainternmed.2019.4624

In Reply On behalf of my coauthors, I write to report errors in our article, “Representativeness of Randomized Clinical Trial Cohorts in End-stage Kidney Disease: A Meta-analysis,”1 that was published online in July 8, 2019, in JAMA Internal Medicine. In that article, we reported on a meta-analysis of 189 randomized clinical trials (RCTs) comprising 80 104 participants to determine whether participants in large, multicenter dialysis trials were similar to the general population undergoing dialysis in terms of age, comorbidities, and mortality rate. We found that “participants in large, multicenter RCTs of patients with end-stage kidney disease undergoing dialysis are younger, have a different pattern of comorbidities, and have a lower mortality rate than the general population of patients undergoing dialysis.”

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words