The ClinicalTrials.gov results database addresses problems with the published literature including publication bias, incomplete reporting of outcome measures and adverse events, and lack of transparency regarding the prespecified trial protocol. Submissions to ClinicalTrials.gov must contain a complete set of minimum results data elements. Entries undergo a quality-control review process based on criteria drawn from fundamental scientific principles, legal requirements, and experience operating the database.1
Zarin DA. The Culture of Trial Results Reporting at Academic Medical Centers. JAMA Intern Med. 2020;180(2):319–320. doi:10.1001/jamainternmed.2019.4200
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.