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Comment & Response
December 2019

Safety of the Use of Radioactive Iodine in Patients With Hyperthyroidism

Author Affiliations
  • 1Department of Diagnostic Radiology, Brooke Army Medical Center, San Antonio, Texas
JAMA Intern Med. 2019;179(12):1737-1738. doi:10.1001/jamainternmed.2019.5117

To the Editor We have concerns about the recently published Original Investigation by Kitahara and colleagues.1 Radioactive iodine (RAI) is an effective and safe therapy that has been used in the treatment of hyperthyroidism for more than 78 years.2-4 Unfortunately, Kitahara and colleagues1 report an increased risk of solid tumor development, which leads referring clinicians and patients to question a safe and effective treatment, namely RAI, for alternative therapies. In this letter, we outline our concerns with the article and recommend careful evaluation of the article data before any changes in patient management are made.

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