[Skip to Navigation]
Comment & Response
February 2020

Epidural Catheter Use and Further Issues in Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant

Author Affiliations
  • 1Coagulation Service and Thrombosis Research Unit, San Raffaele Scientific Institute, Milano, Italy
JAMA Intern Med. 2020;180(2):332-333. doi:10.1001/jamainternmed.2019.5864

To the Editor In 240 BC, and just by using shadows and his brain, Eratosthenes, an ancient Greek scientist, calculated the circumference of the Earth with an approximation of less than 0.1%. Such ingenuity cannot be found in the recently published study by Douketis and colleagues.1 The authors’ conclusions are that a simple, standardized perioperative management strategy without heparin bridging or measurement of coagulation function is associated with low rates of major bleeding and arterial thrombosis. However, the data presented do not appear to support these conclusions.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words