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Comment & Response
February 2020

Hypertension and Unlikely Causality in the Association Between Soft Drink Consumption and Mortality

Author Affiliations
  • 1Department of Internal Medicine, School of Medicine, Universidade do Vale do Taquari, Lajeado, Brazil
  • 2Postgraduate Studies Program in Cardiology, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
JAMA Intern Med. 2020;180(2):335. doi:10.1001/jamainternmed.2019.6102

To the Editor In a long follow-up multinational cohort study performed by Mullee and colleagues,1 in a large sample of European adults, consumption of soft drinks was positively associated with mortality. Both, sugar-sweetened and artificially sweetened soft drinks were associated with risk of death from cerebrovascular or heart disease, particularly the latter. Compared with consumption of fewer than 1 glass per month, intake of 2 or more glasses per day of artificially sweetened soft drinks rendered a significant 26% and 52% increase in all-cause and circulatory disease deaths, respectively.

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