[Skip to Navigation]
March 2, 2020

Updated Hepatitis C Virus Screening Recommendation—A Step Forward

Author Affiliations
  • 1Division of Gastroenterology, Department of Medicine, School of Medicine, University of California, San Francisco
JAMA Intern Med. 2020;180(5):637-639. doi:10.1001/jamainternmed.2019.7334

Hepatitis C virus (HCV) is the most common blood-borne pathogen in the United States, with an estimated 2.4 million people in the US living with HCV, and leads to substantial morbidity and mortality.1 Between 2003 and 2013, the number of HCV-associated deaths in the US exceeded that of the top 60 other notifiable infectious conditions combined.2 Moreover, prior to 2014, only half of people living with HCV were aware that they were infected, and just 9% had been treated and cured.3 In 2013, the US Preventive Services Task Force (USPSTF) recommended screening for HCV infection in persons at high risk for infection and one-time screening in adults born between 1945 and 1965.4 In 2020, the USPSTF has updated its recommendation,5 as well as the evidence report and systematic review,6 to expand the ages for screening to all adults aged 18 to 79 years (B recommendation) and concluded with moderate certainty that implementing such screening will have substantial net benefit. The updated recommendation aligns with joint American Association for the Study of Liver Diseases–Infectious Diseases Society of America recommendations for one-time HCV testing in all adults 18 years or older.7 Recent developments inform the updated USPSTF HCV screening recommendation.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words