Acute pancreatitis is the most common major complication of endoscopic retrograde cholangiopancreatography (ERCP), occurring in 3% to 15% of cases and in up to 40% of procedures if preventive measures are not used. About 5% of patients who develop pancreatitis after ERCP have a severe course, characterized by local and systemic complications, prolonged hospitalization, and occasional death.1 Considering that about 600 000 ERCPs are performed annually in the US, ERCP-related pancreatitis is an important and costly problem.
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Elmunzer BJ, Hernandez I, Gellad WF. The Skyrocketing Cost of Rectal Indomethacin. JAMA Intern Med. 2020;180(5):631–632. doi:10.1001/jamainternmed.2020.0099
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