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Comment & Response
June 15, 2020

Clinical Uncertainty—Reply

Author Affiliations
  • 1University of Wisconsin School of Medicine and Public Health, Madison
  • 2Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  • 3Department of Medicine, Sinai Health System and University Health Network, Toronto, Ontario, Canada
  • 4Institute for Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
JAMA Intern Med. 2020;180(8):1131-1132. doi:10.1001/jamainternmed.2020.1686

In Reply We appreciate the thoughtful contribution to the differential diagnosis and recommended investigations offered by Uzoigwe et al regarding the care of the patient mentioned in our article.1 He went on to have a magnetic resonance imaging scan of his ankle in follow-up, which revealed a homogenous, cystic structure in the calcaneus with peripheral rim enhancement and T2 hyperintensity. This finding was consistent with a unicameral bone cyst.2 The magnetic resonance imaging findings did not suggest osteomyelitis or abscess.2,3 The patient’s symptoms completely resolved, further reinforcing the benign nature of these findings.

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