To the Editor We have read with interest the article by Daubert et al1 regarding the prognostic implications of ST changes during a normal exercise echocardiography (Echo) study. In this analysis performed on 15 077 patients, the authors found positive findings on stress electrocardiography (+ECG) with negative findings on exercise Echo (−Echo) in 1286 patients (9.1% of the −Echo studies). These patients had more events during a median follow-up of 7.3 years than patients with −Echo plus −ECG, although these events were mostly unstable angina and revascularization. The authors conclude that these patients may still be at slightly increased risk.
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Peteiro J, Bouzas-Mosquera A. Implications of ST Changes During Normal Echocardiography. JAMA Intern Med. 2020;180(9):1256–1257. doi:10.1001/jamainternmed.2020.1832
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