Multivessel or Culprit Vessel–Only Percutaneous Coronary Intervention for Patients With Acute Myocardial Infarction and Cardiogenic Shock: Real-World Evidence in Support of CULPRIT-SHOCK

Mortality from cardiogenic shock attributable to acute myocardial infarction (AMI) approaches 50%, a figure that has not significantly improved in recent years.¹ One of the only interventions found to improve mortality is urgent reperfusion of the culprit artery. However, 70% to 80% of patients with ischemic cardiogenic shock have multivessel coronary artery disease,¹ and optimal management of nonculprit lesions has been unclear.