Older adults traditionally have been underrepresented in cardiovascular disease (CVD) trials,1,2 requiring extrapolation of evidence from younger populations.3 In response, the National Institutes of Health (NIH) established the Inclusion Across the Lifespan Policy in January 2019 to expand representation of older adults and children in clinical research.4,5 The policy requires NIH studies to include individuals across the lifespan and to justify age-based exclusions. We set out to assess the early impact of this policy for the inclusion of older adults in CVD trials with a variety of funding sources.
Nanna MG, Chen ST, Nelson AJ, Navar AM, Peterson ED. Representation of Older Adults in Cardiovascular Disease Trials Since the Inclusion Across the Lifespan Policy. JAMA Intern Med. Published online September 08, 2020. doi:10.1001/jamainternmed.2020.2750
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