In this issue of JAMA Internal Medicine, Drawz et al1 report data from the Systolic Blood Pressure Intervention Trial (SPRINT) comparing office blood pressure (BP) measured in the trial with office BP obtained during routine clinical practice. SPRINT, which enrolled adults 50 years or older without diabetes or stroke to determine whether a more intensive BP treatment target was beneficial, was stopped early after an interim analysis showed that an office systolic BP (SBP) target of less than 120 mm Hg reduced cardiovascular events and all-cause mortality compared with a standard SBP target of less than 140 mm Hg.2 As in many hypertension trials, office BP was measured using a standardized protocol that included use of an oscillometric device and appropriately sized cuff along with a 5-minute period of rest before BP was measured, proper positioning of the participant, and measurement of and calculating the mean of 3 BP readings.
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Dodson JA, Shimbo D. A Tale of 2 Blood Pressures. JAMA Intern Med. Published online October 12, 2020. doi:10.1001/jamainternmed.2020.5007
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