To the Editor We read with great interest the case presented by Drs Belyavskaya and deSouza1—massive pulmonary embolism mimicking acute ST-segment−elevation myocardial infarction. However, we found that the authors did not understand that electrocardiograms (ECGs) can provide important clues in the diagnosis of pulmonary embolism, although most of these ECG markers are nonspecific and should be read in the context of the clinical picture.