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Original Investigation
June 10, 2024

Lung Cancer Screening in the US, 2022

Author Affiliations
  • 1Surveillance & Health Equity Science, American Cancer Society, Atlanta, Georgia
  • 2Center for Cancer Screening, American Cancer Society, Atlanta, Georgia
JAMA Intern Med. Published online June 10, 2024. doi:10.1001/jamainternmed.2024.1655
Key Points

Question  What was the prevalence of eligible US individuals being up to date with recommended lung cancer screening (LCS) in 2022?

Findings  In this nationwide cross-sectional study of 25 958 individuals eligible for LCS, 18% reported being up to date with LCS overall, but prevalence varied across states (range, 10%-31%). Rates were lower in southern states that also had high LC mortality burden, but state Medicaid expansion and higher LCS capacity levels were associated with higher prevalence of up-to-date LCS.

Meaning  Recommended LCS uptake was low in 2022, and prevalence did not correspond with LC burden across states; however, improving health care access and LCS capacity may be associated with higher rates.

Abstract

Importance  The US Preventive Services Task Force (USPSTF) recommends annual lung cancer screening (LCS) with low-dose computed tomography in high-risk individuals (age 50-80 years, ≥20 pack-years currently smoking or formerly smoked, and quit <15 years ago) for early detection of LC. However, representative state-level LCS data are unavailable nationwide.

Objective  To estimate the contemporary prevalence of up-to-date (UTD) LCS in the US nationwide and across the 50 states and the District of Columbia.

Design, Setting, and Participants  This cross-sectional study used data from the 2022 Behavioral Risk Factor Surveillance System (BRFSS) population-based, nationwide, state-representative survey for respondents aged 50 to 79 years who were eligible for LCS according to the 2021 USPSTF eligibility criteria. Data analysis was performed from October 1, 2023, to March 20, 2024.

Main Outcomes and Measures  The main outcome was self-reported UTD-LCS (defined as past-year) prevalence according to the 2021 USPSTF eligibility criteria in respondents aged 50 to 79 years. Adjusted prevalence ratios (APRs) and 95% CIs compared differences.

Results  Among 25 958 sample respondents eligible for LCS (median [IQR] age, 62 [11] years), 61.5% reported currently smoking, 54.4% were male, 64.4% were aged 60 years or older, and 53.0% had a high school education or less. The UTD-LCS prevalence was 18.1% overall, but varied across states (range, 9.7%-31.0%), with relatively lower levels in southern states characterized by high LC mortality burden. The UTD-LCS prevalence increased with age (50-54 years: 6.7%; 70-79 years: 27.1%) and number of comorbidities (≥3: 24.6%; none: 8.7%). A total of 3.7% of those without insurance and 5.1% of those without a usual source of care were UTD with LCS, but state-level Medicaid expansions (APR, 2.68; 95% CI, 1.30-5.53) and higher screening capacity levels (high vs low: APR, 1.93; 95% CI, 1.36-2.75) were associated with higher UTD-LCS prevalence.

Conclusions and Relevance  This study of data from the 2022 BRFSS found that the overall prevalence of UTD-LCS was low. Disparities were largest according to health care access and geographically across US states, with low prevalence in southern states with high LC burden. The findings suggest that state-based initiatives to expand access to health care and screening facilities may be associated with improved LCS rates and reduced disparities.

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2 Comments for this article
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Ask why screening is limited
Jesse Cole, MD | Hospital
The Medicare paperwork burden for lung cancer screening is burdensome and expensive. It is simply not worth it for small hospitals who actually have the equipment and radiologists to set this program up for only a few patients a month. This is a point none of these ongoing studies ever seems to look into or consider.
CONFLICT OF INTEREST: None Reported
Thoracic Surgery
Frederic Grannis, MD | City of Hope National Medical Center
If one seeks at least one important reason for tragically low uptake of CT screening for lung cancer (LCS), one needs look no further than JAMA Internal Medicine itself. Former editor Rita Redfield has been a fierce and unyielding critic of CT screening for many years. She chaired a meeting of MEDCAC that recommended against implementation of population screening by the Centers for Medicare and Medicaid Services in 2014.

https://www.auntminnie.com/clinical-news/ct/article/15609382/ct-lung-screening-meeting-a-travesty-of-public-health-policy

As recently as 2022, Redfield wrote an opinion piece in a San Francisco newspaper entitled, "A CT scan could save you from lung cancer. But it could
also do more harm than good." By Rita Redberg and Sanket Dhruva April 14, 2022

https://www.sfchronicle.com/opinion/openforum/article/A-CT-scan-could-save-you-from-lung-cancer-But-it-17078936.phpvising against LCS.
CONFLICT OF INTEREST: I am an investigator for IELCAP and have received reimbursements for travel and accommoedations for semi-annual research meetings 2001-present. I have provided paid expert witness testimony against Philip Morris in three medical monitoring class action lawsuits ending 2016
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