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Editor's Correspondence
May 8, 2006

Statins and Fracture: Are All Variables Accounted For?

Arch Intern Med. 2006;166(9):1041-1042. doi:10.1001/archinte.166.9.1041-a

In reporting their findings of an association between statin use and fracture risk reduction, Scranton et al1 acknowledged that they did not consider the use of thiazide diuretics as a confounding variable. In explaining why they did not statistically adjust for thiazide diuretic use, the authors erroneously state, “the evidence of their association is limited.”1(p2011)