ANN B.NATTINGERMD, MPH
I disagree with Dr Raggi on the strength of evidence supporting the practice of routine screening for subclinical atherosclerosis among asymptomatic individuals. The principal differences in interpretation of the data are 2-fold: (1) I believe that there is insufficient measurement of risk factors in most of the available prospective cohort studies against which the new information is compared, and (2) I believe that most of the multivariate analyses are inadequate to assess the true independent prognostic value of this new information.
O’Malley PG. Rebuttal. Arch Intern Med. 2006;166(10):1071–1072. doi:https://doi.org/10.1001/archinte.166.10.1071
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