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Editor's Correspondence
July 23, 2007

Folic Acid and Cognitive Function: What Is the Final Verdict?

Author Affiliations

Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007

Arch Intern Med. 2007;167(14):1555. doi:10.1001/archinte.167.14.1555-a

In their systematic review on pyridoxine hydrochloride (vitamin B6), cyanocobalamin or hydroxycobalamin (vitamin B12), and folic acid supplementation on cognitive function, Balk et al1(p21) concluded that

the evidence does not yet provide adequate evidence of an effect of vitamin B6 or B12 or folic acid supplementation, alone or in combination, on cognitive function testing in people with either normal or impaired cognitive function.