We recently reported the effects of garlic products on blood lipids among adults with moderately elevated LDL-C in a placebo-controlled randomized controlled trial.1 These 3 products—dried powdered garlic, aged garlic extract, and mashed raw garlic—were extensively chemically characterized before and throughout the intervention.2 Monthly blood samples were collected for 6 months for 192 randomized participants (87%-90% retention per treatment group). None of these garlic products had statistically or clinically significant effects on LDL-C or plasma lipid concentrations. We believe that this trial successfully addressed the limitations of many previous trials examining possible effects of garlic on blood lipid levels.3,4
Gardner C, Lawson LD, Block E. Effects of Garlic on Cholesterol: Not Down But Not Out Either—Reply. Arch Intern Med. 2008;168(1):112–113. doi:10.1001/archinternmed.2007.14
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