In their letter, Hillman and colleagues write that we failed to “include the results of the largest cluster randomized control trial yet conducted.” Indeed, we did include the results of their MERIT study in our meta-analysis on rapid response teams (RRTs).1 In fact, their landmark study remains, to date, the only multicenter, randomized trial of RRTs.2 Importantly, MERIT found no differences in rates of unexpected cardiac arrests or deaths between control and intervention hospitals.
Chan PS, Nallamothu BK, Sasson C. Meta-analysis for Rapid Response Teams—Reply. Arch Intern Med. 2010;170(11):996–997. doi:10.1001/archinternmed.2010.179