Community-acquired pneumonia (CAP) is a common, morbid, and mortal disease, and appropriate antibiotic therapy remains the cornerstone of management. Patients hospitalized with CAP can be infected with both typical and atypical bacterial organisms.1 Most evidence indicates that clinical features (signs and symptoms) at presentation are not specific enough to consistently predict the causative agent.1 Therefore, absent unique epidemiologic characteristics, the overwhelming majority of patients must be treated empirically. To improve the quality of care and decrease practice variability, professional societies have published guidelines for the management of CAP, including recommending specific empirical antibiotic regimens.
Sharpe BA. Guideline-Recommended Antibiotics in Community-Acquired Pneumonia: Not Perfect, but Good. Arch Intern Med. 2009;169(16):1462–1464. doi:10.1001/archinternmed.2009.272
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