Ischemic stroke is a common and often devastating condition that can cause significant disability or death. In light of the dire consequences of a completed stroke, the search for improved predictive models and new markers to identify patients at heightened risk is well justified. Such high-risk patients would be candidates for proven stroke-prevention therapies including aspirin,1 antihypertensive medications, and HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors.2
Greenland P, O’Malley PG. When Is a New Prediction Marker Useful? A Consideration of Lipoprotein-Associated Phospholipase A2 and C-Reactive Protein for Stroke Risk. Arch Intern Med. 2005;165(21):2454–2456. doi:10.1001/archinte.165.21.2454
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