The article by Abrahamsen et al,1 suggests that our article on proton pump inhibitor (PPI) use and fracture risk,2 has “suggested a causal relationship.”
This is not a correct interpretation of our findings: although we found a small overall association between PPI use and fracture, we emphasized that “there was inverse association between duration of use of acid-suppressive medications and fracture risk, which does not support adverse effects on the bone.”2(p1997)
de Vries F. Inverse Association Between Duration of Use of Acid-Suppressive Medications and Fracture Risk. Arch Intern Med. 2011;171(11):1044. doi:10.1001/archinternmed.2011.226
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: