Tomic et al1 describe the effectiveness of a rigorous infection control program to prevent nosocomial spread of methicillin-resistant Staphylococcus aureus (MRSA) in a hospital in Slovenia. After 1 year of observations, the promotion of hand hygiene, active surveillance cultures at admission to identify MRSA carriers, strict application of barrier precautions for patients with MRSA, eradication of MRSA carriage, and continuous education of health care workers on appropriate hygiene procedures was implemented, and the incidence of MRSA was measured during 4 years.