Copyright 2005 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2005
The article by Stenson et al1 determined that the prevalence of celiac disease in their bone clinic was 3.4% compared with 0.2% in nonosteoporotic control patients after screening tests. One of the tests was the 25-hydroxyvitamin D level, and in Table 31(p395) the authors state the normal range to be 0 to 55 ng/mL (0-137.3 nmol/L) but provide no references. Although the lower limit of normal for 25-hydroxyvitamin D is controversial, several references2,3 use 12 to 15 ng/mL (30.0-37.4 nmol/L) as the lower limit of normal. Of the 9 patients found to have celiac disease, 6 had levels of 15 ng/mL or lower (≤37.4 nmol/L), suggesting possible 25-hydroxyvitamin D deficiency. What percentage of the control group had levels of 15 ng/mL or lower (≤37.4 nmol/L)? Urinary calcium levels would have been interesting but remain controversial in the workup of secondary osteoporosis.
Hoyt R. Celiac Disease and Osteoporosis. Arch Intern Med. 2005;165(16):1922–1923. doi:10.1001/archinte.165.16.1922-b